Beta blockers in non-cardiac surgery: haemodynamic data needed.

1930 www.thelancet.com Vol 372 December 6, 2008 or febuxostat). Enhanced understanding of pathophysiological mechanisms might lead to improved drugs, with reduced potential for side-eff ects compared with today’s uricosurics. Even more exciting is the idea that responding to the defects of these transporter proteins might have further benefi cial eff ects, because they could also transport other molecules besides urate. Some studies have suggested that the association between metabolic syndrome and gout is not only caused by diet and personal behaviour. If this association holds true, we might have a better understanding of some of the most relevant medical problems of our time.